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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP1
All Species:
25.45
Human Site:
S262
Identified Species:
46.67
UniProt:
P29972
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29972
NP_932766.1
269
28526
S262
L
D
A
D
D
I
N
S
R
V
E
M
K
P
K
Chimpanzee
Pan troglodytes
XP_519026
269
28548
S262
L
D
A
D
D
I
N
S
R
V
E
M
K
P
K
Rhesus Macaque
Macaca mulatta
XP_001084411
269
28522
S262
L
D
A
D
D
I
N
S
R
V
E
M
K
P
K
Dog
Lupus familis
XP_543678
271
28842
S261
R
Q
S
V
E
L
H
S
P
Q
S
L
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q02013
269
28775
S262
L
D
A
D
D
I
N
S
R
V
E
M
K
P
K
Rat
Rattus norvegicus
P29975
269
28838
S262
L
D
A
D
D
I
N
S
R
V
E
M
K
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521059
168
18146
Chicken
Gallus gallus
NP_001034542
270
28478
S263
L
E
G
D
D
M
N
S
R
V
E
M
K
P
K
Frog
Xenopus laevis
NP_001085391
274
29077
A267
Y
E
I
D
D
D
H
A
R
V
E
M
K
P
K
Zebra Danio
Brachydanio rerio
NP_996942
260
27399
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9XF58
285
29817
A274
Q
Y
V
L
R
A
S
A
A
K
L
G
S
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43286
287
30456
S277
L
R
A
S
G
S
K
S
L
G
S
F
R
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
44.6
N.A.
94
93.3
N.A.
50.9
85.5
74.8
59.4
N.A.
36.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.5
63
N.A.
95.5
95.1
N.A.
58.3
91.8
86.8
75
N.A.
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
80
60
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
0
93.3
80
0
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
41.8
N.A.
N.A.
Protein Similarity:
N.A.
55.4
N.A.
56.1
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
0
0
8
0
16
8
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
0
54
54
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
8
0
0
0
0
0
54
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
0
8
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
39
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
0
0
54
0
54
% K
% Leu:
54
0
0
8
0
8
0
0
8
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
54
0
0
0
% M
% Asn:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
8
54
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
54
0
0
0
8
8
0
% R
% Ser:
0
0
8
8
0
8
8
62
0
0
16
0
8
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _